ea0016p527 | Obesity | ECE2008
St-Pierre David H
, Cianflone Katherine
, Smith Jessica
, Lu Huiling
, Coderre Lise
, Karelis Antony D
, Imbeault Pascal
, Lavoie Jean-Marc
, Rabasa-Lhoret Remi
Objective: Acylation Simulating Protein (ASP) has been shown to regulate lipid clearance and glucose uptake in adipose tissue. In vitro studies demonstrate that insulin stimulates ASP secretion from adipocytes. Individuals with obesity and/or metabolic disturbances (insulin resistance and type 2 diabetes) have increased plasma ASP, suggesting ASP resistance. Therefore, the present study evaluates whether ASP levels are influenced by the metabolic profile of overweight and obes...